Figure 1.

Simplified overall reaction and characteristic simulation of (a) a basic catalyst, (b) an allosteric catalyst, and (c) a cooperative catalyst. Signal and auxiliary species are colored in black and gray, respectively. Each plot shows the relative concentration of output Y at 1 h versus that of input X. The standard concentration (1×) is 100 nM. The initial concentrations of the gate GY and fuel F are 1× and 2×, respectively. The initial concentration of the activator A is shown in the legend.