Products of Andrographis paniculata are available in multiple forms on the market, but the preparations are not yet well standardized to offer the expected effectiveness. |
The diterpene lactones identified as active compounds in this species are poorly soluble in water and show slow dissolution rates. Their solubility behavior presents a major challenge to achieving a pharmacological effect. |
Suitable pharmaceutical technologies improve the dissolution rate and oral bioavailability of diterpene lactones from A. paniculata formulations. |