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. 2021 Nov 11;17(11):e1010026. doi: 10.1371/journal.ppat.1010026

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© 2021 Nguyen et al

This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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Fig 3 — (A) IgM/IgD flow cytometry profile of MZB and FoB during infection (left panels) and FoB-CD23 expression histogram plot during infection (right panel). One representative data set of 9 individual measurements is shown. (B) Log normalized expression of Cd1d1, Cr2, Ighd, and Fcer2a in spleen B cell populations in UMAP projection. (C) MZB and FoB populations UMAP visualization, with proportional pie-chart representation of population at 3 different time points. Pie-chart diameters are normalized for each population size. (D-E) Left panels: Differential gene expression analysis of MZB/FoB at 14dpi versus Naïve. Dash lines display cut-off of P value (0.05). Right panels: Gene ontology analysis of top 100 differential expressed genes of MZB/FoB at 14dpi.