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. 2021 Nov 23;16(11):e0260463. doi: 10.1371/journal.pone.0260463

Table 5. Change in the mean FRAP antioxidant capacity, phenolic and flavonoid concentration of two bottles each of nine herbal supplements*.

Water Extractions Methanol Extractions
Supplier Supplement Bottle A(TE) P (GAE) F (CE) A (TE) P (GAE) F (CE)
Spring Valley^ Echinacea 1 -
Spring Valley^ Echinacea 2 - - -
Sundown Naturals Echinacea 1 - -
Sundown Naturals Echinacea 2 - - -
Nature’s Way Echinacea Goldenseal 1 - - - -
Nature’s Way Echinacea Goldenseal 2 - - -
Spring Valley^ Echinacea Goldenseal 1 - - -
Spring Valley^ Echinacea Goldenseal 2 - -
Spring Valley Turmeric 1 - - -
Spring Valley Turmeric 2 - - - -
Sundown Naturals Turmeric 1 - - - - -
Sundown Naturals Turmeric 2 - - - - -
Nature’s Way Valerian 1 - - -
Nature’s Way Valerian 2 - - -
Spring Valley^ Valerian 1 - -
Spring Valley^ Valerian 2 - - -
Sundown Naturals Valerian 1 - - -
Sundown Naturals Valerian 2 - - -

* Assays were conducted on two bottles each 5 capsules per bottle two years after the initial supplement testing conducted January to February 2019. Data was analyzed with a one-tailed t-test with an α level of 0.05 and a test value of < -25% change.

^Supplements that had expired at the time of the retest.