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. 2021 Feb 23;2:100023. doi: 10.1016/j.crmicr.2021.100023

Fig. 1.

Fig. 1

P2 × 7 is important for the control of infection by P. gingivalis and F. nucleatum in vivo. (A) Relative levels of IL-1β mRNA are shown in gingival tissue using real-time PCR. (B) Levels of IL-1β are shown in the mandible using ELISA. (C) Relative amount of P. gingivalis DNA in gingival tissue by real-time PCR. (D) Relative amount of F. nucleatum DNA are shown in the gingival tissue by real-time PCR of C57BL/6 (WT) and P2 × 7−/- animals infected or not infected orally with 109 CFU of each strain of P. gingivalis (ATCC 33,277) and F. nucleatum (ATCC 25,586). The data represent the mean ± SEM. (A) and (B)n = 4; (C) WT FnPg = 9, P2 × 7−/- FnPg = 6; (D) WT FnPg = 7, P2 × 7−/- FnPg = 6. The data were analyzed using one-way ANOVA, followed by the Tukey test. * p <0.05; **p <0.005. Pg: Porphyromonas gingivalis; Fn: Fusobacterium nucleatum.