Figure 2.

Effects of AU on the LTA-induced expression COX-2, IL-1β, and TNF-α in RAW 264.7 macrophages. (a)–(d) Cells were untreated or pretreated with AU (5 and 10 μM) for 30 min and then stimulated with LTA (5 μg/ml) for 24 h. COX-2, IL-1β, and TNF-α were detected as described in Section 2. The values shown are the means ± S.E.M. of four independent experiments. ^∗∗P < 0.01 and ^∗∗∗P < 0.001 vs. the control cells; ^#P < 0.05, ^##P < 0.01, and ^###P < 0.001 vs. LTA-stimulated cells.