Table 3.
The methodological quality of the non-randomised studies (NRSs) using the Newcastle-Ottawa Scale (NOS)
| The Newcastle-Ottawa Scale (NOS) of NRS studies | ||
|---|---|---|
|
| ||
| Study | Outcomes assessed | Remarks |
| Schriber (1994) [17] | NE, ac GVHD II-IV | Poor quality |
| Berger (1999) [18] | All outcomes | Good quality |
| Ozcan (2001) [19] | All outcomes | Good quality |
| Remberger (2003) [2] | All outcomes | Good quality |
| Ringdén (2004) [20] | NE, ac GVHD II-IV, ch GVHD, OS | Good quality for NE, Poor for others |
| Khoury (2006) [21] | All outcomes except PE | Good quality |
| Ringden (2010) [3] | All outcomes | Good quality |
| Singh (2021) [22] | All outcomes | Good quality |
| George (2020) [23] | NE, HS | Good quality |
NE: Neutrophil engraftment; ac GVHD: Acute graft vs host disease; ch GVHD: Chronic graft vs host disease; PE: Platelet engraftment; OS: Overall survival, HS: Hospital stay.