Appendix 3.
Eggers Test
| Analysis | Eggers’ test of the intercept | Publication bias | |||
|---|---|---|---|---|---|
| NE duration | |||||
| NRS with outliers | intercept | 95% CI | t | p | No |
| -3.872 | -22.68 - 14.93 | -0.404 | 0.694 | ||
| Eggers’ test does not indicate the presence of funnel plot asymmetry. | |||||
| NRS with no outliers | intercept | 95% CI | t | p | No |
| 1.731 | -0.56 - 4.02 | 1.484 | 0.198 | ||
| Eggers’ test does not indicate the presence of funnel plot asymmetry. | |||||
| RCT with outliers | intercept | 95% CI | t | p | Yes |
| -8.323 | -12.11 - -4.53 | -4.302 | 0.013 | ||
| Eggers’ test indicates the presence of funnel plot asymmetry. | |||||
| RCT with no outliers | intercept | 95% CI | t | p | No |
| -9.712 | -59.48 - 40.05 | -0.383 | 0.767 | ||
| Eggers’ test does not indicate the presence of funnel plot asymmetry. | |||||
| NE probability | |||||
| NRS | intercept | 95% CI | t | p | No |
| 0.937 | -0.75 - 2.63 | 1.088 | 0.318 | ||
| Eggers’ test does not indicate the presence of funnel plot asymmetry. | |||||
| RCT - only one study | - not done - - | ||||
| GVHD | |||||
| RCT | intercept | 95% CI | t | p | No |
| -1.108 | -2.53 - 0.31 | -1.533 | 0.163 | ||
| Eggers’ test does not indicate the presence of funnel plot asymmetry. | |||||
| NRS | intercept | 95% CI | t | p | No |
| -0.058 | -1.4 - 1.29 | -0.084 | 0.934 | ||
| Eggers’ test does not indicate the presence of funnel plot asymmetry. | |||||
| Survival | |||||
| NRS | intercept | 95% CI | t | p | No |
| 2.389 | 0.53 - 4.25 | 2.522 | 0.0652 | ||
| Eggers’ test does not indicate the presence of funnel plot asymmetry. | |||||
| RCT | intercept | 95% CI | t | p | No |
| 0.754 | 0.31 - 1.2 | 3.302 | 0.0807 | ||
| Eggers’ test does not indicate the presence of funnel plot asymmetry. | |||||
| Hospital stay | |||||
| NRS with outliers | intercept | 95% CI | t | p | No |
| 7.727 | -18.76 - 34.22 | 0.572 | 0.585 | ||
| Eggers’ test does not indicate the presence of funnel plot asymmetry. | |||||
| RCT with outliers | intercept | 95% CI | t | p | No |
| -13.629 | -23.4 - -3.86 | -2.734 | 0.112 | ||
| Eggers’ test does not indicate the presence of funnel plot asymmetry. | |||||
| NRS with no outliers | intercept | 95% CI | t | p | No |
| -0.013 | -10.76 - 10.73 | -0.002 | 0.998 | ||
| Eggers’ test does not indicate the presence of funnel plot asymmetry. | |||||
| RCT with no outliers | intercept | 95% CI | t | p | No |
| -19.899 | -64.11 - 24.31 | -0.882 | 0.5397882 | ||
| Eggers’ test does not indicate the presence of funnel plot asymmetry. | |||||
| Platelet | |||||
| NRS | intercept | 95% CI | t | p | No |
| 14.605 | -27.66 - 56.87 | 0.677 | 0.568 | ||
| Eggers’ test does not indicate the presence of funnel plot asymmetry. | |||||
| RCT | intercept | 95% CI | t | p | No |
| 2.161 | -7.26 - 11.59 | 0.449 | 0.7311 | ||
| Eggers’ test does not indicate the presence of funnel plot asymmetry. | |||||