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. 2021 Nov 24;12(3):830–840. doi: 10.1016/j.jceh.2021.11.009

Table 2.

Cox-Proportional Analysis of Variables Associated With Mortality in the Whole Cohort and After Propensity Score Matching (PSM).

Whole cohort PSM
P-value
Characteristics Univariate analysis HR (95% CI)
Age (years) 1.014 (0.996–1.033) 0.135 1.017 (0.991–1.044) 0.201
Sex
Females 1 1
Male 0.955 (0.544–1.675) 0.872 1.065 (0.492–2.307) 0.872
Diabetes, yes 0.943 (0.537–1.655) 0.838 0.980 (0.467–2.059) 0.958
Etiology
Others 1 1
Alcohol 0.846 (0.544–1.316) 0.458 0.878 (0.469–1.645) 0.684
Hemoglobin (g/dL) 0.959 (0.871–1.057) 0.402 0.912 (0.793–1.050) 0.201
TLC (per mm3) 0.991 (0.947–1.036) 0.692 1.002 (0.945–1.063) 0.950
Platelet count ( × 103/mm3) 1.000 (0.997–1.002) 0.760 0.999 (0.996–1.003) 0.651
INR 1.191 (1.062–1.337) 0.003 1.133 (0.945–1.359) 0.178
Total bilirubin (mg/dL) 1.041 (0.989–1.097) 0.123 1.095 (1.025–1.169) 0.007
Creatinine (mg/dl) 1.219 (1.065–1.397) 0.004 1.239 (0.931–1.648) 0.142
AST (IU/L) 1.001 (0.998–1.003) 0.631 0.998 (0.991–1.005) 0.625
ALT (IU/L) 1.000 (0.998–1.003) 0.811 0.996 (0.984–1.008) 0.504
Alk P (IU/L) 1.002 (1.001–1.003) 1.001 (0.999–1.003) 0.287
Albumin (g/dL) 0.598 (0.424–0.842) 0.003 0.512 (0.325–0.807) 0.004
CTP 1.224 (1.122–1.336) <0.001 1.307 (1.154–1.480) <0.001
Child class
A 1 1
B 2.684 (1.277–5.642) 0.009 4.415 (1.493–13.055) 0.007
C 4.680 (2.268–9.657) <0.001 8.098 (2.750–23.848) <0.001
MELD 1.068 (1.034–1.103) <0.001 1.074 (1.029–1.121) 0.001
COVID-19
No 1 1
Yes 0.775 (0.474–1.268) 0.331 1.224 (0.663–2.263) 0.520

Abbreviations: TLC, total leukocyte count; INR, international normalized ratio; ALT, alanine aminotransferase; Alk P, alkaline phosphatase; AST, aspartate aminotransferase; CTP, Child-Turcotte-Pugh; MELD, model for end-stage liver disease.