Table 5.
Clinical manifestations of early- and late-onset colorectal cancer patients in 2008-2019
|
Variables
|
< 50-years-old, n (%)
|
≥ 50-years-old, n (%)
|
Total, n (%)
|
P
|
| Smoking | 69 (33.7) | 114 (39.3) | 183 (37) | 0.199 |
| Parental history of CRC | 8 (3.9) | 4 (1.4) | 12 (2.4) | 0.072 |
| Other family history of CRC | 6 (2.9) | 8 (2.8) | 14 (2.8) | 0.911 |
| Suspicion of FAP | 4 (2.0) | 6 (2.1) | 10 (2.0) | 0.927 |
| Suspicion of HNPCCa | 19 (9.3) | 12 (4.1) | 31 (6.3) | < 0.05 |
| BMI | ||||
| Underweightc | 71 (34.6) | 58 (20.0) | 129 (26.1) | < 0.001 |
| Normoweight | 71 (34.6) | 101 (34.8) | 172 (34.7) | 0.521 |
| Overweight and obeseb | 63 (30.7) | 131 (45.2) | 194 (39.2) | < 0.005 |
| Comorbidities | ||||
| Diabetes mellitusc | 8 (3.9) | 53 (18.3) | 61 (12.3) | < 0.001 |
| Hypertensionc | 7 (3.4) | 73 (25.2) | 80 (16.2) | < 0.001 |
a
Chi-square test, P < 0.05.
b
Fisher’s exact test, P < 0.005.
c
Fisher’s exact test, P < 0.001.
BMI: Body mass index; CRC: Colorectal cancer; FAP: Familial adenomatous polyposis; HNPCC: Hereditary nonpolyposis colorectal cancer.