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. 2021 Nov 23;12:6796. doi: 10.1038/s41467-021-27092-z

Fig. 7. D2 receptor activation in the LS is necessary for VTA DAergic activity to increase aggression.

Fig. 7

a The schematic diagram for local infusions of sulpiride in the LS followed by optogenetic stimulation (blue) of the VTA to evoke in vivo non-projection specific DA release. b Local sulpiride infusion into the LS prevents aggression elicited by optogenetic activation of VTA DAergic activity. c No difference in locomotion was detected between the groups following local infusion of sulpiride in the LS. Time-fighting, for individual pairs, is broken down by d, e treatment and f, g stimulation condition. *P < 0.05; ***P < 0.001 compared with their respective controls; mean ± SEM; n = 11 pairs (b, d–g) and 20/group (c). VEH, vehicle.