Table 4.
The expression levels (mean RQ value) of the studied genes and miRNAs in COPD patients with/without the exacerbation history.
| Exacerbation history | Without the exacerbation history in last 12 months | p value | |
|---|---|---|---|
| Induced sputum | |||
| Genes | |||
| IL-6 | 0.393 ± 0.667 | 0.287 ± 0.708 | 0.96 |
| IL6ST | 0.565 ± 0.545 | 0.161 ± 0.126 | 0.03* |
| PIAS3 | 4.230 ± 5.737 | 0.255 ± 0.458 | 0.02 |
| STAT3 | 0.505 ± 0.310 | 0.976 ± 1.099 | 0.19 |
| miRNA | |||
| miRNA-1 | 0.019 ± 0.014 | 0.573 ± 1.408 | 0.55 |
| miRNA-106b | 15.892 ± 10.020 | 10.835 ± 11.899 | 0.27 |
| miRNA-155 | 9.959 ± 6.933 | 166.499 ± 393.684 | 0.1 |
| Peripheral blood (PB) lymphocytes | |||
| Genes | |||
| IL-6 | 0.007 ± 0.004 | 0.007 ± 0.005 | 0.62 |
| IL6ST | 0.163 ± 0.132 | 0.525 ± 0.482 | 0.19 |
| PIAS3 | 0.265 ± 0.180 | 0.539 ± 0.02 | 0.60 |
| STAT3 | 0.191 ± 0.103 | 0.262 ± 0.227 | 0.64 |
| miRNA | |||
| miRNA-1 | 0.561 ± 0.034 | 0.637 ± 0.900 | 0.32 |
| miRNA-106b | 0.01 ± 0.0008 | 0.019 ± 0.018 | 0.36 |
| miRNA-155 | 1.738 ± 0.823 | 1.641 ± 0.931 | 0.64 |