Table 1.
Additional main biological parameters before and after FP-induced shock in sheep.
| Baseline | Shock | p-values | ||
|---|---|---|---|---|
| Lactate (mmol/L) * | 0.8 (0.5–0.9) | 2.2 (2–2.4) | < 0.0001 | |
| ScvO2 (%) † | 81.9 ± 4.7 | 64.1 ± 5.9 | < 0.0001 | |
| Base excess (mmol/L) † | 8.1 ± 3.3 | 2.5 ± 4.1 | < 0.0001 | |
| Tn T (pg/mL) * | 154.5 (137.5–191.1) | 168.5 (151.0–194.8) | 0.002 | |
| Cortisol (ng/mL) † | 292.8 ± 198.4 | 3479 ± 2175 | < 0.0001 | |
| AVP (pg/mL) † | 16.6 ± 5.3 | 18.8 ± 7.7 | 0.015 | |
| Urinary KIM-1 (pg/mL) † | 75.9 ± 25.1 | 102.7 ± 31.7 | 0.022 | |
| Creatinine clearance (mL/min) † | 147.2 ± 70.7 | 1.8 ± 1.7 | < 0.0001 | |
| EVLW (mL) † | 413.1 ± 93.5 | 502.9 ± 104.6 | 0.011 | |
| VO2 (mL/min) † | 13.2 ± 3.6 | 11.1 ± 2.3 | 0.01 | |
All data are expressed as the median [25–75 interquartile range] ⁎ or mean ± SD †, as appropriate, for n = 18 sheep. Variation was compared with a paired t-test or the Mann Whitney U test.
ScvO2 central venous oxygen saturation, Tn T troponin T, AVP arginine vasopressin, KIM-1 kidney injury molecule-1, EVLW extravascular lung water, VO2 oxygen consumption.