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. 2021 Nov 23;12(12):1103. doi: 10.1038/s41419-021-04309-z

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 1 — a The correlation between HOMER3-AS1 (AC005932.1) expression and overall survival according to TCGA LIHC dataset, analyzed by GEPIA. b Kaplan-Meier survival analysis of the correlation between HOMER3-AS1 expression and overall survival in our HCC cohort. n = 68, p = 0.0441, HR = 1.924 by log-rank test. c HOMER3-AS1 expression in 68 pairs of HCC tissues and adjacent noncancerous liver tissues was measured by qRT-PCR. ****p < 0.0001 by Wilcoxon matched-pairs signed-rank test. d HOMER3-AS1 expression in immortalized human liver cell lines THLE-2 and THLE-3, and human HCC cell lines SK-HEP-1, SNU-398, and Huh7 were measured by qRT-PCR. Results are presented as mean ± SD based on three independent experiments. ****p < 0.0001, ns, not significant, by one-way ANOVA followed by Dunnett’s multiple comparisons test.