TABLE IV.

Engraftment and subsequent unplanned cell infusions

	First HCT, patients (n = 57)	Second HCT, patients (n = 8)	Third HCT, patients (n = 1)
Engraftment
Primary graft failure	2 (4)	0	0
Secondary graft failure	7 (12)	1 (13)	0
Unstable chimerism or threatened graft failure (not progressing to graft failure)	4 (7)	2 (25)	0
Poor graft function	9 (16)	3 (38)	0
Subsequent unplanned cell infusion, no. of patients*	18 (32)	4 (50)	0
Donor lymphocyte infusion†	7 (12)	2 (25)	0
Repeat HCT‡	8 (14)	1 (13)	0
Peripheral blood stem cell boost§	5 (9)	1 (13)	0

Values are n or n (%).

^*A total of 43 subsequent unplanned cell infusions were administered.

^†A total of 24 unplanned donor lymphocyte infusions were administered, for mixed chimerism (n = 18), viral infection (n = 2), lymphoma relapse (n = 2), poor graft function (n = 1), promoting immune reconstitution (n = 1).

^‡Indications for repeat HCT included graft failure (n = 6), mixed chimerism (n = 2), and lymphoma relapse (n = 1).

^§A total of 10 stem cell boosts were administered, for poor graft function (n = 9) and to promote immune reconstitution (n = 1, included CD3⁺ add back).