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. 2021 Nov 14;27(42):7340–7349. doi: 10.3748/wjg.v27.i42.7340

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©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.

This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial.

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Alpha diversity indices (Shannon index) of hepatocellular carcinoma patients based on treatment and prognosis. A: The Shannon index of the non-responders on admission (T0) was not significantly lower than that of the responders (P = 0.14); B: The Shannon index of the non-responders was significantly lower than that of the responders after nivolumab therapy (T1); C: Nivolumab therapy did not alter the Shannon index. HCC: Hepatocellular carcinoma.