Table 2.
Patient demographics and treatment details based on fiducial-based image-guided radiotherapy and standard image-guided radiotherapy
|
Variables
|
F-IGRT
|
S-IGRT
|
|
|
Median/n, range/%
|
Median/n, range/%
|
||
| Age | 77.4, 57.5-88.0 | 77.3, 64.8-85.4 | |
| Male | 19, 70.4 | 1, 25.0 | |
| Site of cancer | Oesophageal | 18, 62.1 | 3, 75.0 |
| GOJ (Siewert I/II) | 0, 0.0 | 1, 25.0 | |
| GOJ (Siewert III) | 2, 7.4 | 0, 0.0 | |
| Gastric | 7, 25.9 | 0, 0.0 | |
| Type of cancer | Oesophageal SCC | 13, 48.1 | 3, 75.0 |
| Oesophageal adenocarcinoma | 5, 18.5 | 1, 25.0 | |
| Gastric adenocarcinoma | 9, 33.3 | 0, 0.0 | |
| Endoscopy data | Patients with both proximal and distal fiducial placed | 22, 81.5 | 2, 50.0 |
| Patients with solely proximal or distal fiducials placed | 5, 18.5 | 2, 50.0 | |
| ECOG | 0 | 11, 40.7 | 2, 50.0 |
| 1 | 9, 33.3 | 2, 50.0 | |
| 2 | 7, 25.9 | 0, 0.0 | |
| Stages1 | LN negative without distant metastasis | 18, 66.7 | 4, 100.0 |
| LN positive without distant metastasis | 6, 22.2 | 0, 0.0 | |
| Distant metastasis present | 3, 11.1 | 0, 0.0 | |
| Treatment details | Time to treatment (d) | 19.0, 9.0-44 | 14 .0, 9.0-17.0 |
| Curative intent | 20, 74.1 | 4, 100.0 | |
| Palliative intent | 7, 25.9 | 0, 0.0 | |
| Dose (Grays) | 50, 25.2-55 | 47.7, 41.4-54 | |
| Fraction | 25, 10-30 | 26.5, 23-30 | |
| Duration (d) | 30, 14-47 | 37, 30-39 | |
| Chemotherapy | 14, 51.9 | 4, 100.0 | |
1
Staging as per American Joint Committee on Cancer 8th edition. T-stage was not available for all patients as endoscopic ultrasound is not routinely performed at our center.
F-IGRT: Fiducial-based image-guided radiotherapy; S-IGRT: Standard image-guided radiotherapy; SCC: Squamous cell carcinoma; ECOG: Eastern Cooperative Oncology Group; GOJ: Gastro-oesophageal junction; LN: Lymph Node.