Table 1.
Comparisons of different demographic, clinical, and paraclinical data of the subjects between the case and control groups in the univariate model
| Variables | Case Group (n=50) | Control Group (n=50) | Univariate | ||
|---|---|---|---|---|---|
| P value | OR (95% confidence interval) | ||||
| Age (year) (mean±SD) | 40.7±13.58 | 41.8±13.56 | 0.69 | 1.006 (0.97-1.03) | |
| Sex (%) | Male | 32 (64) | 32 (64) | - | 1 |
| Female | 18 (36) | 18 (36) | 1 | 1 (0.44-2.26) | |
| Etiology (%) | Others | 32 (64) | 29 (58) | 1 | |
| Hypertension | 18 (36) | 21 (42) | 0.54 | 0.78 (0.35-1.74) | |
| Length of pre-transplantation dialysis (month, mean±SD) | 15.0±12 | 17.5±12 | 0.56 | 0.99 (0.96-1.02) | |
| Donor type (%) | Cadaver | 48 (96) | 49 (98) | - | 1 |
| Living | 2 (4) | 1 (2) | 0.56 | 0.49 (0.04-5.58) | |
| Donor age (year) (mean±SD) | 36.38±14.18 | 36.14±15.19 | 0.34 | 1.01 (0.98-1.04) | |
| Donor sex (%) | Male | 41 (82) | 36 (72) | - | 1 |
| Female | 9 (18) | 14 (28) | 0.24 | 0.56 (0.22-1.46) | |
| Cold ischemia time (hour), median (interquartile range) | 5.13 (4.5) | 7.7 (3.0) | 0.98 | 0.99 (0.89-1.11) | |
| Panel reactive antibody (%) | Negative | 44 (88) | 47 (94) | 1 | |
| Positive | 6 (12) | 3 (6) | 0.303 | 2.14 (0.50-9.07) | |
| Receiving anti-thymocyte globulin as an induction of immunosuppression (%) | Yes | 44 (88) | 36 (72) | - | 1 |
| No | 6 (12) | 14 (28) | 0.051 | 2.85 (0.995-8.173) | |
| Anti-thymocyte globulin dose (mg), median (interquartile range) | 375 (300) | 310 (300) | 0.39 | 0.99 (0.99-1.001) | |
| Immunosuppressive maintenance regimen (%) | Tacrolimus+Mycophenolate+Prednisolone | 42 (84) | 4 (72) | --- | 1 |
| Others | 8 (16) | 46 (28) | 0.152 | 2.042 (0.77-5.42) | |
| Glomerular filtration rate at hospital admission (mL/min, median+interquartile range) | 7.5±0.0 | 8.4±0.25 | 0.19 | 1.06 (0.97-1.16) | |
| Cyclosporine trough level (ng/dL, mean±SD) | 711.873±184.1 | 422.41±149.62 | 0.37 | 0.99 (0.98-1.007) | |
| Tacrolimus trough level (ng/dL, mean±SD) | 7.45±3.18 | 5.56±2.12 | 0.01 | 0.76 (0.61-0.95) | |
| Delayed graft function (%) | Yes | 7 (14) | 4 (8) | --- | 1 |
| No | 43 (86) | 46 (92) | -0.343 | 1.87 (0.51-6.85) | |
SD: Standard deviation; OR: Odds ratio; A univariate logistic regression analysis was used.