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. 2021 Nov 24;11(1):293–304. doi: 10.1007/s40121-021-00514-7

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License, which permits any non-commercial use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by-nc/4.0/.

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Fig. 1 — Histograms presenting the distribution of age, hospitalization time, time before CCP and levels of WBC, ferritin, CRP and IL-6 on day 1. The total number of patients analyzed was 267; however, when laboratory tests were not performed on a given day, data were excluded. Documentation about WBC level was available for n = 158 patients, about ferritin for n = 126 patients, about CRP for n = 187 patients and about IL-6 for n = 104 patients. Nonetheless, all statistical comparisons were adequately powered