TABLE 2.
Effect of probucol and lovastatin on monocrotaline‐induced changes in right ventricle antioxidant enzyme activities at 4‐week post‐MCT treatment in rats
Group | GSHPx (nmol/mg protein) | SOD (U/mg protein) | CAT (U/mg protein) |
---|---|---|---|
CONT | 44.7 ± 4.6 | 36.4 ± 2.0 | 29.3 ± 2.8 |
MCT | 23.6 ± 3.4* | 34.2 ± 3.8 | 31.4 ± 3.1 |
PROB | 50.4 ± 2.4 | 52.6 ± 5.4 † | 35.4 ± 2.7 |
PROB + MCT | 62.6 ± 4.2 † | 59.3 ± 4.0 † | 27.3 ± 3.2 |
LOV | 41.2 ± 3.4 | 37.6 ± 2.6 | 31.4 ± 3.7 |
LOV + MCT | 24.4 ± 2.4* | 42.3 ± 3.7 | 33.6 ± 4.2 |
Data are mean ± SEM of 5–6 animals.
Abbreviations: CAT, catalase; GSHPx, glutathione peroxidase; SOD, superoxide dismutase.
Significantly different (p < 0.05) from the CONT, PROB, PROB + MCT, and LOV groups.
Significantly different (p < 0.05) from the CONT, MCT, LOV, and LOV + MCT groups. All other legends are similar to that in Table 1.