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. 2021 Oct 31;14(4):475–484. doi: 10.15283/ijsc21031

Table 1.

Biochemical markers of liver fibrosis and inflammation according to HLSC strains and HLSC transplantation scheme

AST ALT APRI
Baseline Post 14w CCl4 Baseline Post 14w CCl4 Baseline Post 14w CCl4
Control 341.50 117.17 188.50 49.17* 0.66 0.48
HLSC7 573.50 93.00* 742.33 65.67* 1.06 0.24*
HLSC15 411 139* 437 85* 0.76 0.25*
HLSC26 538 105* 629 56* 0.98 0.25*
Control 341.50 117.17 188.50 49.17* 0.66 0.48
HLSCx 573.50 93.00* 742.33 65.67* 1.06 0.24*
HLSC2x 436.00 92.40 465.80 49.60 0.93 0.28
HLSCxx 262.40 120.00 249.40 54.40* 0.50 0.18

APRI (AST to platelet ratio index)=(AST/upper limit of normal for AST)×100/platelet count (×109/l), *p<0.05.

HLSCx: single dose, single transplant; HLSC2x: double dose, single transplant; HLSCxx: single dose, tandem transplants.