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. 2021 May 7;69(3):247–255. doi: 10.3164/jcbn.20-185

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This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives License (http://creativecommons.org/licenses/by-nc-nd/4.0/).

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Fig. 4. — We confirmed effects of CoQ₁₀ on IL-6, IL-8, and p21 gene expression in fibroblasts of SIPS model. The SASP (such as IL-6, IL-8, and p21) related to aging was increased by the addition of H₂O₂, while it decreased the mRNA levels of IL-6, IL-8, and p21 with CoQ₁₀ treatment. Results are means ± SD. n = 3–6, **p<0.01.