Figure 7.

The bilayered constructs facilitated the regeneration of osteochondral tissues in vivo (n = 6). The grafts were sampled 3 months after operation. (A) Gross observations of defect repair at 3 months for the control group, pristine-bilayered construct group, and GF-bilayered construct group (scale bar: 4 mm). (B) Hematoxylin and eosin (H & E) staining of repaired cartilage at 3 months (N, normal cartilage; R, repair cartilage; blue arrows, typical cartilage lacunae structures; black arrows, the repair boundary of the cartilage surface; scale bar: 200 μm). (C) Masson staining of repaired cartilage at 3 months (scale bar: 200 μm). (D) Safranin-O/fast green staining of repaired cartilage at 3 months (scale bar: 200 μm).