Table 4.
Multivariate analysis with Cox proportional hazards model on risk factors for prognosis of NPC patients.
| Factor | SE | Wald | p | EXP(B) | 95% CI | |
|---|---|---|---|---|---|---|
| Upper limit | Lower limit | |||||
| Age | 0.145 | 0.014 | 0.905 | 1.017 | 0.765 | 1.353 |
| Gender | 0.146 | 0.416 | 0.519 | 1.099 | 0.826 | 1.462 |
| Pathological staging | 0.148 | 0.143 | 0.705 | 0.945 | 0.707 | 1.264 |
| T-staging | 0.189 | 3.276 | 0.070 | 1.408 | 0.972 | 2.039 |
| N-staging | 0.184 | 0.111 | 0.740 | 1.063 | 0.742 | 1.523 |
| Clinical staging | 0.182 | 0.148 | 0.700 | 1.073 | 0.751 | 1.533 |
| Distant metastasis | 0.069 | 4.087 | 0.043 | 1.150 | 1.004 | 1.316 |
| AKT expression | 0.185 | 5.499 | 0.019 | 1.543 | 1.074 | 2.217 |
| mTOR expression | 0.261 | 10.907 | 0.001 | 2.365 | 1.419 | 3.943 |
| P70S6K expression | 0.178 | 7.610 | 0.006 | 1.635 | 1.153 | 2.318 |
NPC, nasopharyngeal carcinoma; mTOR, mammalian target of rapamycin; P70S6K, p70 ribosomal S6 kinase; SE, standard error; CI, confidence interval.