Kaplan-Meier curves for hospitalization in the breakthrough cohort (fully vaccinated patients with breakthrough infections) with hospitalizations followed starting from the day of breakthrough infections up to October 8, 2021, and in the no-breakthrough cohort (fully vaccinated patients without breakthrough infections) with hospitalizations followed starting at 14 days after full vaccinations up to October 8, 2021. The 2 cohorts were propensity score matched for demographics, adverse socioeconomic determinants of health, transplants, comorbidities, characteristics of multiple myeloma (status, stage, lymphocyte counts), COVID-19-related medications, multiple myeloma treatments (chemotherapy, target therapy, radiation therapy, and stem cell transplant), and vaccine types. Shaded areas represent 95% CIs.