Table 1.
Predicted quantities for D = 10 Gy x m=5 fraction SBRT of lung cancer cell lines
| Cell lines | SW1573 24 h DP | HX147 | HX149M | HX144 | HC12 |
|---|---|---|---|---|---|
| y in Gy–1 | 0.90 | 0.33 | 0.44 | 0.45 | 0.59 |
| n | 12.00 | 3.20 | 4.00 | 4.00 | 4.50 |
| S(D) | 0.0015 | 0.1058 | 0.0471 | 0.0412 | 0.0124 |
| RS(O) in Gy–1 | 0.075 | 0.104 | 0.110 | 0.114 | 0.131 |
| GRS in Gy–1 | 0.33 | 0.20 | 0.24 | 0.25 | 0.30 |
| BED in Gy | 38.97 | 35.50 | 37.27 | 37.68 | 39.75 |
| EQD2 in Gy | 185.45 | 86.57 | 100.96 | 101.23 | 108.50 |
| TCP a | 100.0% | 87.6% | 99.8% | 99.9% | 100.0% |
| TCP b | 100.0% | 26.5% | 97.7% | 98.8% | 100.0% |
| TCP c | 100.0% | 0.0% | 79.3% | 88.9% | 100.0% |
| D50 a in Gy | 4.72 | 8.92 | 7.23 | 7.01 | 5.61 |
| D50 b in Gy | 5.30 | 10.42 | 8.38 | 8.12 | 6.47 |
| D50 b in Gy | 5.85 | 11.88 | 9.48 | 9.19 | 7.30 |
| BED50 a in Gy | 12.50 | 29.83 | 23.08 | 22.37 | 17.48 |
| BED50 b in Gy | 15.40 | 37.67 | 29.01 | 28.11 | 21.92 |
| BED50 c in Gy | 18.17 | 45.13 | 34.65 | 33.59 | 26.15 |
| Γ50 a in Gy–1 | 0.27 | 0.10 | 0.14 | 0.14 | 0.18 |
| Γ50 b in Gy–1 | 0.29 | 0.11 | 0.14 | 0.15 | 0.19 |
| Γ50 c in Gy–1 | 0.29 | 0.11 | 0.15 | 0.15 | 0.19 |
| D3fx in Gy | 14.83 | 14.67 | 14.69 | 14.74 | 14.99 |
BED, biologically effective dose; SBRT, stereotactic body radiotherapy; TCP, tumour control probability.
These values are calculated with a total tumour cell number of No = 104.
These values are calculated with a total tumour cell number of No = 105.
These values are calculated with a total tumour cell number of No = 106.