Table 2.
Patients with del(20)(q) as sole anomaly in BM: definition of the deletion by a-CGH (patients 1–8) or FISH (patients 11 and 12)
| Patient | Bands | Deletion start (bp) | Deletion stop (bp) | % Abnormal cells |
|---|---|---|---|---|
| 1 | q11.21-q13.13 | 31,954,597 | 48,328,296 | 36% |
| 3 | q11.2-q13.2 | 31,720,622 | 53,559,811 | 26% |
| 5 | q11.21-q13.13 | 30,849,566 | 49,398,586 | 29% |
| 6 | q11.21-q13.13 | 30,889,915 | 47,912,299 | 74% |
| 7 | q11.21-q13.13 | 31,412,080 | 49,339,757 | 39% |
| 8 | q11.21-q13.32 | 31,671,222 | 57,911,624 | 36% |
| 11 | q11.22-q12a | – | – | 5.6%b |
| 12 | q11.22-q12a | – | – | 2.9%c |
The percentage of abnormal cells is calculated from a-CGH results, except for patients 11 and 12
aResult obtained by double color FISH with the bac probes RP11-17F3 and RP11-29E13: the deletion therefore is at least from 33,797,020 to 40,857,566 bp
b% from FISH results: 1/16 mitoses and 18/321 nuclei
c% from FISH result: 9/309 nuclei