Table 2.
Univariate and multivariate analysis of patients with macroscopic peritoneal involvement treated with upfront surgery
| Variable | Univariate | Multivariate | |
|---|---|---|---|
| HR | P | ||
| Age | |||
| > 68 (ref.) | 0.33 | 1.04 | 0.59 |
| < 68 | |||
| Gender | |||
| Female | 0.22 | 1.17 | 0.80 |
| Male (ref) | |||
| Tumor location | |||
| Upper (ref.) | |||
| Body | 0.53 | 1.03 | 0.10 |
| Antrum | |||
| Surgery type | |||
| Subtotal gastrectomy | |||
| Total gastrectomy (ref.) | 0.36 | 2.35 | 0.07 |
| Lymphadenectomy | |||
| D1 (ref.) | |||
| D2 | 0.04 | 2.76 | 0.03 |
| PLUS | |||
| pT | |||
| 3 | |||
| 4a (ref.) | 0.002 | 2.14 | 0.12 |
| 4b | |||
| pN | |||
| N1 (ref) | |||
| N2 | 0.003 | 1.49 | 0.3 |
| N3 | |||
| Lauren’s istotype | |||
| Intestinal | 0.56 | 2.35 | 0.08 |
| Diffuse | |||
| HIPEC | |||
| Yes | 0.07 | 0.34 | 0.11 |
| No | |||
| Surgical radicality | |||
| R0 (ref.) | |||
| R1 | 0.01 | 1.68 | 0.03 |
| R2 | |||
| Peritoneal involvement | |||
| P1 (ref) | |||
| P2 | 0.023 | 1.03 | 0.03 |
| P3 | |||
| Adjuvant chemotherapy | |||
| Yes | 0.34 | 1.17 | 0.73 |
| No | |||