Table 5.
Results of the Gene-enrichment and Functional Annotation Analysis for mRNAs of interest identified by LRSC
| KEGG pathway | Count | % | P-value/EASE | Genes |
|---|---|---|---|---|
| Aminoacyl-tRNA biosynthesis | 7 | 3.06 | 1.40E−04 | YARS, LARS, PARS2, MARS, TARS, HARS, QRSL1 |
| Cell cycle | 8 | 3.49 | 7.49E−04 | ORC1, PLK1, CUL1, TTK, MCM6, SMC1A, BUB1, MAD2L1 |
| Purine metabolism | 7 | 3.06 | 2.02E−02 | POLA1, ADSL, RRM2, PRIM1, PPAT, PDE2A, GMPS |
| Oocyte meiosis | 5 | 2.18 | 4.63E−02 | PLK1, CUL1, SMC1A, BUB1, MAD2L1 |
| RNA transport | 6 | 2.62 | 5.86E−02 | NDC1, NUP155, GEMIN5, GEMIN8, EIF2S1, NUP37 |
| Alanine, aspartate and glutamate metabolism | 3 | 1.31 | 6.76E−02 | ADSL, PPAT, CAD |
| DNA replication | 3 | 1.31 | 7.11E−02 | POLA1, PRIM1, MCM6 |
A summary of the results of the Gene-enrichment and Functional Annotation Analysis (GEFA) for the mRNAs of interest identified by LRSC. In all, 231 overlapping genes were only consistently identified by LRSC, 229 of these genes mapped in DAVID and were included in the GEFA