Table 6.
Results of the survival analysis of the 75 significant mRNAs identified by LRSC
| Entrez ID | Symbol | TCGA median log-rank | LIRI-JP median log-rank |
|---|---|---|---|
| 5036 | PA2G4 | 1.47E−03 | 5.30E−06 |
| 3838 | KPNA2 | 1.40E−02 | 1.30E−05 |
| 57405 | SPC25 | 3.05E−02 | 1.55E−05 |
| 8550 | MAPKAPK5 | 2.79E−02 | 4.44E−05 |
| 55143 | CDCA8 | 2.61E−02 | 7.28E−05 |
| 1776 | DNASE1L3 | 2.16E−02 | 2.49E−04 |
| 54538 | ROBO4 | 1.37E−02 | 2.98E−04 |
| 5138 | PDE2A | 6.89E−03 | 3.17E−04 |
| 25956 | SEC31B | 1.85E−03 | 3.22E−04 |
| 6421 | SFPQ | 8.09E−04 | 1.37E−03 |
| 55706 | NDC1 | 4.12E−02 | 2.01E−03 |
| 51380 | CSAD | 1.70E−02 | 2.02E−03 |
| 2665 | GDI2 | 4.79E−02 | 2.78E−03 |
| 8520 | HAT1 | 1.35E−02 | 3.04E−03 |
| 2519 | FUCA2 | 4.19E−02 | 3.06E−03 |
| 51026 | GOLT1B | 2.92E−03 | 6.00E−03 |
| 29889 | GNL2 | 2.63E−03 | 7.94E−03 |
| 790 | CAD | 2.63E−02 | 1.03E−02 |
| 8243 | SMC1A | 2.27E−02 | 1.07E−02 |
| 339327 | ZNF546 | 2.67E−02 | 1.14E−02 |
| 1478 | CSTF2 | 6.14E−03 | 1.50E−02 |
| 79022 | TMEM106C | 4.48E−04 | 1.64E−02 |
| 84253 | GARNL3 | 2.01E−02 | 2.14E−02 |
| 9361 | LONP1 | 2.18E−02 | 2.27E−02 |
| 23381 | SMG5 | 2.95E−02 | 2.67E−02 |
| 9532 | BAG2 | 1.32E−02 | 2.74E−02 |
| 55131 | RBM28 | 1.23E−02 | 2.91E−02 |
| 4038 | LRP4 | 1.06E−03 | 4.07E−02 |
| 83941 | TM2D1 | 3.81E−02 | 4.84E−02 |
| 90355 | c5orf30 | 8.13E−03 | 6.17E−02 |
| 23657 | SLC7A11 | 2.26E−03 | 7.32E−02 |
| 10489 | LRRC41 | 4.73E−02 | 8.07E−02 |
| 65244 | SPATS2 | 3.16E−02 | 8.16E−02 |
| 3913 | LAMB2 | 8.27E−03 | 8.52E−02 |
| 7444 | VRK2 | 1.95E−02 | 8.66E−02 |
| 8807 | IL18RAP | 1.34E−03 | 8.75E−02 |
| 79739 | TTLL7 | 3.94E−02 | 8.88E−02 |
| 2764 | GMFB | 7.68E−03 | 1.00E−01 |
| 51253 | MRPL37 | 1.81E−02 | 1.02E−01 |
| 1965 | EIF2S1 | 5.40E−03 | 1.22E−01 |
| 127544 | RNF19B | 6.66E−03 | 1.32E−01 |
| 60682 | SMAP1 | 4.86E−03 | 1.46E−01 |
| 3931 | LCAT | 1.92E−02 | 1.48E−01 |
| 56829 | ZC3HAV1 | 4.36E−02 | 1.70E−01 |
| 5514 | PPP1R10 | 4.66E−02 | 1.81E−01 |
| 8565 | YARS | 5.54E−04 | 1.90E−01 |
| 55056 | FLJ10038 | 3.73E−02 | 2.03E−01 |
| 10626 | TRIM16 | 2.97E−02 | 2.04E−01 |
| 10487 | CAP1 | 4.08E−02 | 2.29E−01 |
| 10570 | DPYSL4 | 1.36E−02 | 2.35E−01 |
| 201229 | LYRM9 | 5.58E−03 | 2.66E−01 |
| 4359 | MPZ | 3.41E−02 | 3.00E−01 |
| 79989 | TTC26 | 8.51E−04 | 3.53E−01 |
| 308 | ANXA5 | 1.85E−04 | 4.24E−01 |
| 57181 | SLC39A10 | 2.64E−02 | 4.35E−01 |
| 5256 | PHKA2 | 4.46E−02 | 4.40E−01 |
| 6611 | SMS | 1.48E−02 | 4.49E−01 |
| 95681 | CEP41 | 1.59E−02 | 4.70E−01 |
| 64175 | P3H1 | 1.38E−03 | 4.81E−01 |
| 6897 | TARS | 2.13E−02 | 5.20E−01 |
| 10206 | TRIM13 | 1.47E−02 | 5.23E−01 |
| 55212 | BBS7 | 9.59E−03 | 5.35E−01 |
| 3939 | LDHA | 3.08E−04 | 5.37E−01 |
| 201798 | TIGD4 | 3.85E−02 | 5.43E−01 |
| 169200 | TMEM64 | 8.06E−03 | 5.66E−01 |
| 84725 | PLEKHA8 | 3.97E−02 | 5.96E−01 |
| 5097 | PCDH1 | 1.37E−02 | 6.23E−01 |
| 84085 | FBXO30 | 6.83E−03 | 6.56E−01 |
| 8790 | FPGT | 2.03E−02 | 7.22E−01 |
| 79879 | CCDC134 | 2.67E−04 | 8.10E−01 |
| 3312 | HSPA8 | 3.49E−03 | 9.06E−01 |
| 11096 | ADAMTS5 | 4.80E−04 | 9.14E−01 |
| 51520 | LARS | 2.06E−03 | 9.46E−01 |
| 80723 | SLC35G2 | 3.38E−02 | 9.46E−01 |
| 90110 | LOC90110 | 4.47E−02 | NA |
A summary of the results of the survival analysis of the mRNAs identified by LRSC. A total of 75 genes were prognostic in the TCGA HCC cohort as indicated by a significant log-rank result; 29 of these were also prognostic in the LIRI-JP cohort, indicated here in bold. NA—Not applicable for testing as gene not available in validation dataset