TABLE 4.
Diagnostic accuracy of INH resistance prediction by RPA/nanopore sequencing, using phenotypic drug susceptibility testing as the reference test
| Result using index method (RPA/nanopore)a | No. of strains with indicated result using reference method (DST)b |
||||
|---|---|---|---|---|---|
| R | S | Total | Sensitivity (95% CI) | Specificity (95% CI) | |
| R | 25 | 0 | 25 | 100.00 (86.28–100.00) | 100.00 (39.76–100.00) |
| S | 0 | 4 | 4 | ||
| Total | 25 | 4 | 29 | ||
a
RPA, recombinase polymerase amplification; R, RIF resistant; S, RIF susceptible.
b
DST, drug susceptibility testing.