Table II.
Major SNP cases identified in the seven patients with SLE.
| SNP | Chr | Gene | Class | SNP type |
|---|---|---|---|---|
| rs3024866 | Chr2 | STAT4 | A | IV |
| rs17266594 | Chr4 | BANK1 | A | IV |
| rs10516487 | Chr4 | BANK1 | A | MV |
| rs280519 | Chr19 | TYK2 | A | IV |
| rs25487 | Chr19 | XRCC1 | A | MV |
| rs7530511 | Chr1 | IL23R | A | MV |
| rs549908 | Chr11 | IL18 | A | SV |
| rs3803800 | Chr17 | TNFSF13 | A | MV |
| rs344555 | Chr19 | C3 | A | IV |
| rs2476601 | Chr1 | PTPN22 | A | MV/IV |
| rs1061622 | Chr1 | TNFRSF1B | A | ICV |
| rs2230365 | Chr6 | NFKBIL1 | A | SV |
| rs419788 | Chr6 | SKIV2L | A | IV/UV |
| rs3813946 | Chr1 | CR2 | A | 5′UTRV |
| rs1048971 | Chr1 | CR2 | A | SV |
| rs2246614 | Chr11 | CDHR5 | A | MV |
| rs2255336 | Chr12 | KLRC4-KLRK1 | A | MV/NCTV |
| rs17615 | Chr1 | CR2 | A | MV |
| rs945635 | Chr1 | FCRL3 | A | NCTV |
| rs3733197 | Chr4 | BANK1 | A | MV |
| rs2069763 | Chr4 | IL2 | A | SV |
| rs352140 | Chr3 | TLR9 | A | SV |
| rs315952 | Chr2 | IL1RN | A | MV |
| rs2326369 | Chr20 | MAVS | A | SV |
| rs315951 | Chr2 | IL1RN | A | 3′UTRV |
| rs6133 | Chr1 | SELP | A | MV |
| rs763361 | Chr18 | CD226 | A | MV |
| rs2076530 | Chr6 | BTNL2 | A | MV/IV |
| rs4986938 | Chr14 | ESR2 | A | NCTV |
| rs2230201 | Chr19 | C3 | A | SV |
| rs3803665 | Chr16 | ZNF423 | A | SV |
| rs11552708 | Chr17 | TNFSF13 | A | MV/IV |
| rs6259 | Chr17 | SHBG | A | MV |
| rs3025000 | Chr6 | VEGFA | A | IV |
| rs513349 | Chr6 | BAK1 | B | IV |
| rs2229634 | Chr6 | ITPR3 | B | SV |
| rs7097397 | Chr10 | WDFY4 | B | MV |
| rs1061501 | Chr11 | IRF7 | B | SV |
| rs13181 | Chr19 | ERCC2 | B | StG/DV |
| rs20563 | Chr1 | LAMC1 | B | MV |
| rs4308977 | Chr1 | CR2 | B | MV |
| rs17616 | Chr1 | CR2 | B | MV |
| rs12150220 | Chr17 | NLRP1 | B | MV |
| rs396991 | Chr1 | FCGR3A | B | MV |
| rs1799793 | Chr19 | ERCC2 | B | MV |
| rs1801274 | Chr1 | FCGR2A | B | MV |
| rs3775291 | Chr4 | TLR3 | B | MV |
| rs3184504 | Chr12 | SH2B3 | B | MV |
| rs2279003 | Chr19 | MYO9B | B | SV |
| rs1782455 | Chr1 | MASP2 | C | SV/IV |
| rs6695096 | Chr1 | MASP2 | C | IV |
| rs11203366 | Chr1 | PADI4 | C | MV |
| rs11203367 | Chr1 | PADI4 | C | MV |
| rs874881 | Chr1 | PADI4 | C | MV |
| rs1748033 | Chr1 | PADI4 | C | MV |
| rs3790434 | Chr1 | LEPR | C | IV |
| rs6025 | Chr1 | F5 | C | MV |
| rs1137100 | Chr1 | LEPR | C | MV |
| rs2243188 | Chr1 | IL19 | C | IV/NCTV |
| rs3806268 | Chr1 | NLRP3 | C | SV |
| rs3747517 | Chr2 | IFIH1 | C | MV |
| rs2204640 | Chr2 | HECW2 | C | IV |
| rs708035 | Chr3 | IRAK2 | C | MV |
| rs818819 | Chr3 | SLC22A14 | C | MV |
| rs1137101 | Chr1 | LEPR | C | MV |
| rs1295686 | Chr5 | IL13 | C | IV |
| rs20541 | Chr5 | IL13 | C | MV |
| rs12522248 | Chr5 | HAVCR1 | C | MV |
| rs2075800 | Chr6 | HSPA1L | C | MV |
| rs1225944 | Chr6 | BLOC1S5-TXNDC5 | C | IV |
| rs1045642 | Chr7 | ABCB1 | C | MV |
Class 'A', 'High-associated SNPs'; class 'B', 'Strong-associated SNPs'; class 'C', 'Associated SNPs'; SNPs, single nucleotide polymorphisms; SLE, systemic lupus erythematosus; chr, chromosome; IV, intron variant; MV, missense variant; SV, synonymous variant; 3′UTPV, 3′ UTP variant; 5′UTRV, 5′ UTP variant; NCTV, non-coding transcript variant; StG, stop gained; UV, upstream variant; DV, downstream variant.