Su 2005.
Methods | Allocation: Randomised Endpoint classification: Efficacy study Intervention model: Parallel assignment Masking: Double‐blind (participant, caregiver, investigator, outcomes assessor) Primary Purpose: treatment |
Participants | Adults aged 18 ‐ 65 years meeting DSM‐IV criteria for MDD |
Interventions | Intervention: DHA/EPA (1.6 ~ 2.8 g/d (5 capsules)) Comparator: placebo (5 g/d (5 capsules)) |
Outcomes | Primary: HDRS Secondary: BDI; Adverse events |
Notes | No response from PI |
BDI: Beck depression inventory BNF: British National Formulary CDI: Children's depression inventory CGI: Clinical global impression DHA: docosahexaenoic acid DSM‐IV: Diagnostic and Statistical Manual of Mental Disorders, Fourth edition EPA: eicosapentaenoic acid HDRS: Hamilton depression rating scale MADRS: Montgomery‐Asberg Depression Rating Scale MDD: major depressive disorder MMSE: Mini‐Mental State Examination SSRI: selective serotonin reuptake inhibiting