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. 2021 Nov 24;2021(11):CD004692. doi: 10.1002/14651858.CD004692.pub5

Su 2005.

Methods Allocation: Randomised
Endpoint classification: Efficacy study
Intervention model: Parallel assignment
Masking: Double‐blind (participant, caregiver, investigator, outcomes assessor)
Primary Purpose: treatment
Participants Adults aged 18 ‐ 65 years meeting DSM‐IV criteria for MDD
Interventions Intervention: DHA/EPA (1.6 ~ 2.8 g/d (5 capsules))
Comparator: placebo (5 g/d (5 capsules))
Outcomes Primary: HDRS
Secondary: BDI; Adverse events
Notes No response from PI

BDI: Beck depression inventory
BNF: British National Formulary
CDI: Children's depression inventory
CGI: Clinical global impression
DHA: docosahexaenoic acid
DSM‐IV: Diagnostic and Statistical Manual of Mental Disorders, Fourth edition
EPA: eicosapentaenoic acid
HDRS: Hamilton depression rating scale
MADRS: Montgomery‐Asberg Depression Rating Scale
MDD: major depressive disorder
MMSE: Mini‐Mental State Examination
SSRI: selective serotonin reuptake inhibiting