Amminger 2013.

Study name	Youth Depression Alleviation: A randomised controlled trial of omega‐3 fatty acids (fish oil) for major depressive disorder in young people (YoDA‐F)
Methods	Randomised placebo‐controlled trial
Participants	Participants aged 15 ‐ 25 years, seeking help for psychological distress A score between 11 and 20 on the QIDS‐A17‐C at first contact with the service AND after 1 week (plus 1 ‐ 5 days if the client is unable to attend earlier) at the second assessment, or at 2 subsequent (weekly) follow‐up assessments A diagnosis of MDD using the SCID‐I/P
Interventions	Intervention: Cognitive behavioural case management plus 4 capsules of marine fish oil per day (providing approximately 840 mg of EPA, approximately 560 mg of DHA, and approximately 5 mg of Vitamin E) Comparator: Cognitive behavioural case management plus 4 capsules of placebo per day (approximately 700 mg paraffin oil)
Outcomes	Primary: Change in depressive symptoms as assessed by QIDS‐A17‐C between baseline and 12 weeks Secondary: Change in depressive symptoms as assessed by QIDS‐A17‐C between baseline and 26 weeks, Remission rate at 12 and 26 week follow‐up, Changes to symptomology and psychosocial functioning assessed across a range of domains assessed at baseline and weeks 4, 8, 12, and 26
Starting date	February 2014
Contact information	G Paul Amminger, Orygen Youth Health Research Centre
Notes	ACTRN12613001352796