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Conjugation and in vitro evaluation of 111In-GFP-G1-TAT uptake. (A) Schematic diagram outlaying approach to conjugate monoclonal antibody GFP-G1 with CPP TAT and chelating agent Bn-DTPA using strain-promoted azide–alkyne cycloaddition–based click chemistry. (B) In vitro radiointernalization assay revealing correlation between 111In-GFP-G1-TAT uptake and H2B-EGFP expression.
