Table 5.

Cancer Types and Exposure Units used to Evaluate Potential Exposure Dependence of the Association between Cannabis Use and Cancer Risk

Cancer type	Exposure units	Lowest	Intermed	Intermed +	Highest	Ref.
Oral	Joint-years	>0 to <1	1–10	>10	>30	57
Pharyngeal	Joint-years	> 0 to <1	1–10	>10	>30	57
Laryngeal	Joint-years	> 0 to <1	1–10	>10	>30	57
Lung	Joint-years	> 0 to <1	1–10	>10	>30	57
Esophageal	Joint-years	> 0 to <1	1–10	>10	>30	57
HNSCC	Tertile	1	2	3		59
Oral	Joint-years	>0–2	>2–5	>5		61
Pharyngeal	Joint-years	>0–2	>2–5	>5		61
Laryngeal	Joint-years	>0–2	>2–5	>5		61
HNSCC	Ounces/week×years	0–1/16	1/16 to <3	3 to <7.5	7.5+	75
Oral	Joint-years	0–2	2–10	>10		80
Oropharyngeal	Joint-years	0–2	2–10	>10		80
Oral	Times/week	1	1–7	7+		82
Bladder	Times	11–99	100–499	>500		85
N		14	14	14	6

N-values for each exposure group are shown in bold.

Relative risk data associated with these exposure units are presented in Figure 8.

HNSCC, head and neck squamous cell carcinoma.