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. 2021 Nov 23;46(6):E639–E646. doi: 10.1503/jpn.210066

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© 2021 CMA Joule Inc. or its licensors

This is an Open Access article distributed in accordance with the terms of the Creative Commons Attribution (CC BY-NC-ND 4.0) licence, which permits use, distribution and reproduction in any medium, provided that the original publication is properly cited, the use is noncommercial (i.e., research or educational use), and no modifications or adaptations are made. See: https://creativecommons.org/licenses/by-nc-nd/4.0/

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Cortical areas of increased thalamocortical functional connectivity in participants with insomnia compared with healthy controls. (A and B) The seed is the right thalamus. The insomnia group showed increased functional connectivity in the right superior medial frontal area, bilateral middle temporal areas, right parahippocampal gyrus and left rectus (areas in red) with the right thalamus compared with the healthy control group. (C and D) The seed is the left thalamus. The insomnia group showed increased functional connectivity in the left superior parietal area, both mid-temporal poles and left rectus (areas in red) with the left thalamus compared with the healthy control group. The green and red contours represent the left and right seeds of the thalamus, respectively. The statistical threshold was a voxel-wise uncorrected p < 0.001, with a cluster-wise false discovery rate corrected p < 0.05.