Table 2. The incidence and risk factors for herpes zoster.
| Variables | Event | PY | Rate# (95% CI) | Crude HR (95% CI) | Adjusted HR& (95% CI) |
|---|---|---|---|---|---|
| Plantar fascial fibromatosis | |||||
| No | 834 | 105562 | 7.90(7.60, 8.23) | 1.00 | 1.00 |
| Yes | 265 | 26587 | 9.97(9.28, 10.8) | 1.26(1.10, 1.45)** | 1.23(1.07, 1.41)** |
| Age, year | |||||
| ≤ 49 | 250 | 56409 | 4.43(4.17, 4.70) | 1.00 | 1.00 |
| 50–64 | 566 | 54171 | 10.5(9.95, 11.0) | 2.38(2.05, 2.76)*** | 2.21(1.89, 2.57)*** |
| 65+ | 283 | 21568 | 13.1(12.2, 14.3) | 3.01(2.54, 3.57)*** | 2.65(2.21, 3.18)*** |
| Sex | |||||
| Female | 788 | 85062 | 9.26(8.92, 9.66) | 1.40(1.23, 1.60)*** | 1.26(1.10, 1.44)*** |
| Male | 311 | 47087 | 6.60(6.22, 7.01) | 1.00 | 1.00 |
| Comorbidities | |||||
| Diabetes | |||||
| No | 1000 | 124051 | 8.06(7.75, 8.40) | 1.00 | 1.00 |
| Yes | 99 | 8097 | 12.2(10.7, 14.0) | 1.54(1.25, 1.89)*** | 1.07(0.87, 1.33) |
| CAD | |||||
| No | 857 | 113781 | 7.53(7.23, 7.83) | 1.00 | 1.00 |
| Yes | 242 | 18368 | 13.2(12.0, 14.0) | 1.77(1.53, 2.04)*** | 1.25(1.07, 1.46)** |
| Depression | |||||
| No | 1026 | 125644 | 8.17(7.91, 8.48) | 1.00 | 1.00 |
| Yes | 73 | 6505 | 11.2(9.75, 12.9) | 1.43(1.13, 1.82)** | 1.18(0.93, 1.51) |
| Chronic kidney disease | |||||
| No | 1076 | 130543 | 8.24(7.99, 8.57) | 1.00 | 1.00 |
| Yes | 23 | 1605 | 14.3(11.0, 18.7) | 1.80(1.19, 2.73)** | 1.31(0.86, 1.99) |
| Obesity | |||||
| No | 1083 | 129722 | 8.35(8.07, 8.65) | 1.00 | 1.00 |
| Yes | 16 | 2427 | 6.59(5.14, 8.48) | 0.82(0.50, 1.35) | |
| Cancer | |||||
| No | 1062 | 129118 | 8.23(7.91, 8.48) | 1.00 | 1.00 |
| Yes | 37 | 3030 | 12.2(10.1, 14.8) | 1.54(1.11, 2.14)* | 1.18(0.85, 1.65) |
Rate#, incidence rate, per 1,000 person-years; Crude HR, relative hazard ratio; Adjusted HR&, multivariable analysis including age, sex, and comorbidities of diabetes, CAD, depression, chronic kidney disease, and cancer;
*p<0.05,
**p<0.01,
***p<0.001