Table 4. Cox method estimated hazard ratios of herpes zoster associated plantar fascial fibromatosis and comorbidities.

Variables		N	Event (n)	Adjusted HR† (95% CI)	p-value#
Plantar fascial fibromatosis	Diabetes				0.81
No	No	17685	760	1(Reference)
No	Yes	1231	74	1.09(0.85, 1.38)
Yes	No	4422	240	1.24(1.07, 1.43)**
Yes	Yes	307	25	1.38(0.93, 2.06)
Plantar fascial fibromatosis	CAD				0.32
No	No	16317	669	1(Reference)
No	Yes	2599	165	1.12(0.94, 1.34)
Yes	No	3887	188	1.16(0.99, 1.37)
Yes	Yes	842	77	1.63(1.28, 2.08)***
Plantar fascial fibromatosis	Depression				0.50
No	No	17860	780	1(Reference)
No	Yes	1056	54	1.25(0.95, 1.65)
Yes	No	4408	246	1.24(1.08, 1.44)**
Yes	Yes	321	19	1.46(0.92, 2.30)
Plantar fascial fibromatosis	Chronic kidney disease				0.83
No	No	18609	816	1(Reference)
No	Yes	307	18	1.32(0.83, 2.12)
Yes	No	4666	260	1.24(1.08, 1.43)**
Yes	Yes	63	5	1.47(0.61, 3.55)
Plantar fascial fibromatosis	Obesity
No	No	18605	826	1(Reference)	0.56
No	Yes	311	8	0.71(0.35, 1.42)
Yes	No	4526	257	1.24(1.08, 1.43)**
Yes	Yes	203	8	1.15(0.57, 2.30)
Plantar fascial fibromatosis	Cancer				0.69
No	No	18359	805	1(Reference)
No	Yes	557	29	1.21(0.83, 1.75)
Yes	No	4594	257	1.25(1.09, 1.44)**
Yes	Yes	135	8	1.26(0.63, 2.53)

^† Model was adjusted for age and sex;

^#p-value for interaction;

**p<0.01;

***p < 0.001