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. 2021 Nov 24;16(11):e0258170. doi: 10.1371/journal.pone.0258170

Table 4. Summary of meta-analysis.

Table of results for early interventions administered within one month of exposure to a traumatic birth.

Comparison Follow-up and contributing studies Study (no) Sample (n) Relative Risk (95% CI) Std.Mean Diff (95% CI) Grade Rating
Interventions delivered within 72hrs following traumatic birth
Immediate response early psychological Intervention vs CAU
Dosage 1–2 sessions
PTSD symptom severity 4–6 weeks post-partum
Abdollahpour, 2016; Abdollahpour 2019; Azadzadeh 2020; Chiorino 2019; Gamble 2005; Horsch, 2017 [29, 4145]
6 224:258 PP -0.58 Moderate
PTSD symptom severity 12wks weeks post-partum
Abdollahpour, 2016; Abdollahpour 2019; Azadzadeh 2020; Chiorino 2019; Gamble 2005 [29,4143]
5 199:234 PP -1.08 Low
Midwifery led debriefing vs CAU
Dosage 1 x session
PTSD symptom severity 12 weeks post-partum
Abdollahpour, 2019 [41]
1 51:81 PP -0.84 Low
TF-CBT counselling vs active intervention debriefing
Dosage 1 x session
PTSD symptom severity 12 weeks post-partum
Abdollahpour, 2019 [41]
1 47:51 PP -1.45 Low
Early EMDR vs CAU
Dosage 1xsession
PTSD Rates remission 6 weeks post-partum
Chiorino 2019 [44].
PTSD Rates remission 12 weeks post-partum
Chiorino 2019 [44].
1 19:18 2.03 p = 0.03
1.34
P = 0.11
Low
Visuospatial gaming activity
Dosage 1xgame Tetris
Prevalence of intrusive memories 1-week post-partum
Horsch 2017 [45].
1 ITT 29:27
PP 25:24
ITT 0.41
PP -5.46
Low
Early EMDR vs CAU
Dosage 1x session
Prevalence of intrusive memories 12 weeks post-partum
Chiorino 2019 [44].
1 19:18 0.16
P = 0.07
Low
Midwifery led brief counselling intervention
Dosage 2 x sessions
Diagnosis of PTSD 4–6 weeks post-partum
Gamble, 2005 [29].
Diagnosis of PTSD 12 weeks post-partum
Gamble, 2005 [29].
1 50:53 1.13
P = 0.68
0.33
P = 0.08
Low
Interventions delivered
up to 3 wks following traumatic premature birth
Early TF-CBT therapy vs active psychoeducation intervention
Dosage 6–9 sessions
PTSD symptom severity 4–6 weeks post-partum
Shaw, 2013 [48].
1 62:43 ITT -0.10
d = -0.33
adjusted Bonferroni d = 0.41 p = .023
Low
Intervention delivered
33 days following traumatic premature birth
Cues intervention vs Attention Control Comparison
Dosage 6 x sessions Cues Programme
Dosage 6 x contacts with care intervener (active comparison)
PTSD symptom severity: follow up time unclear
Zelkowitz,2011 [50].
1 48:58 -0.10 Low
Intervention self-administered
within 4 weeks of a traumatic birth
Online recorded footage and paper-based Psychoeducation
Dosage unlimited
self-led
Clinical criteria for diagnosis of PTSD 12 weeks
Slade, 2020 [49].
1 336:342 ITT 0.77 p = .40
PP 0.81 p = .67
Moderate