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. 2021 Nov 24;16(11):e0254289. doi: 10.1371/journal.pone.0254289

Table 1. Cases for the enrolled 275 patients.

cases (%) number of examined by IHC/ISH features
progression nuclear grade invasiveness
non-tumor 101 (36.7) 101/10 - - -
PUNLMP 19 (6.9) 19/10 slow very low non-invasive
LGPUC 41 (14.9) 41/15 slow low non-invasive
HGPUC 43 (15.6) 43/18 quick high non-invasive
CIS 39 (14.2) 39/18 quick high non-invasive
IUC 32 (11.6) 32/14 quick high>>low invasive

non-tumor; non-tumor urothelium, PUNLMP; papillary urothelial neoplasm of low malignant potential, LGPUC; low-grade papillary urothelial carcinoma, HGPUC; high-grade urothelial carcinoma, CIS; carcinoma in situ, IUC; infiltrating urothelial carcinoma. IHC; immunohistochemistry, ISH; in situ hybridization.