Figure 4.

CXCL12 was upregulated after OPCs transplantation, which was abolished by the AMD3100. (A) Western blot results of CXCL12, CXCR4, and CXCR7 in the ischemic striatum (n=3/group). *p <0.05, **p <0.01 compared with the OPC group. (B) Photomicrographs of NeuN or GFAP or CD31 (green) and CXCL12 (red) in the perifocal area of ischemic mice. (C) The quantification data of CXCL12 distribution in the different types of cells. (D) Magnified image sections highlighted by the red boxes in (B). Scale bar, 50 μm. Data are presented as means ± SEMs. CXCL12: C-X-C motif chemokine 12, CXCR4: C-X-C chemokine receptor type 4, CXCR7: C-X-C chemokine receptor type 7.