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| Mouse line | Brief description |
| C57BL/6 | WT mouse line |
| A10 cKO | Cre-driven conditional ADAM10 knockout in forebrain neurons (under control of the CamKIIα promotor) (34) |
| Prnp 0/0 | PrP-knockout mouse line (99) |
| tga20 | PrP-overexpressing mouse line (100) |
| 5xFAD | Mouse model for AD-associated amyloid formation |
| 5xFAD/Prnp0/0 | As above but depleted for PrP (by crossing with Prnp0/0 mice) |
