FIG. 6.

Ethidium bromide-stained 6% polyacrylamide gel showing examples of HMA of the NS5b PCR products. Lanes 1, 2, and 3, heteroduplex patterns formed between isolates of subtypes 2b, 3a, and 4a; lanes 4 and 5, HMA of subtypes 2b and 2c and subtypes 3a and 3b; lanes 6 and 7, heteroduplexes formed between different genotypes, 1 and 4 and 3 and 4. Isolates analyzed are shown along the bottom, and the percent divergence between samples is shown along the top. The average HMRs for isolates (0.95), subtypes (0.69), and genotypes (0.55) are indicated on the right (see text for details).