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. 2021 Nov 25;95:50–60. doi: 10.1016/j.ejim.2021.10.031

Table 1B.

Functional values grouped by sex.

All (n = 101) Men (n = 59) Women (n = 42)
Vital parameters
RRsys (mmHg) 130.0 [110.0; 140.0] 130.0 [120.0; 140.0] 12.00 [110.0; 132.5]
RRdia (mmHg) 80.0 [72.3; 90.0] 80.0 [80.0; 90.0] * 80.0 [70.0; 80.0]
Heart rate (1/s) 70.0 [64.0; 75.0] 70.0 [63.0; 74.5] 70.0 [64.5; 76.5]
BMI (kg/m2) 27.5 [25.0; 30.9] 27.8 [24.9; 30.8] 26.8 [24.1; 31.2]
SpO2 (%) 97.0 [96.8; 98.0] 97.0 [96.0; 97.5] 97.0 [97.0; 99.0] *
Lung function/physical capacity
FEV1 (%predicted) 91.6 [82.8; 102.6] 91.1 [82.7; 101.1] 92.29 [82.9; 104.1]
FEV1<LLN (no.) 14 (14%) 8 (14%) 6 (14%)
FEV1/FVC (%) 76.9 [71.8; 81.4] 76.0 [71.5; 80.09] 78.5 [73.1; 84.2]
FEV1/FVC<LLN (no.) 5 (5%) 4 (7%) 1 (2%)
FVC (%predicted) 94.5 [81.9; 101.6] 94.5 [82.9; 100.3] 93.78 [79.9; 101.8]
FVC<LLN (no.) 13 (13%) 8 (14%) 5 (12%)
TLC (%predicted) 109.5 [102.5; 121.7] 105.2 [98.6; 121.1] 111.6 [107.3; 122.1] *
TLC<LLN (no.) 6 (6%) 4 (7%) 2 (5%)
RV/TLC (%predicted) 44.1 [105.7; 126.5] 43.0 [105.6; 126.0] 47.3 [108.3; 129.3]
RV/TLC>ULN (no.) 26 (26%) 10 (17%) 16 (38%) *
6-MWD (%predicted) (n = 99) 101.9 [88.2; 110.9] 101.9 [90.6; 106.2] 101.9 [88.1; 114.7]
6-MWD<LLN (no.) 5 (5%) 5 (9%) 0 (0%)
Laboratory values
Hemoglobin (g/dl) (n = 98) 14.7 [13. 6; 15.6] 15.3 [14.6; 16.2] *** 13.7 [12.8; 14.1]
Leucocytes (x109/l) (n = 98) 6.27 [5.38; 7.26] 6.19 [5.27; 7.24] 6.38 [5.49; 7.66]
Thrombocytes (Gpt/l) (n = 98) 245.5 [212.3; 285.3] 231.5 [185.5; 270.0] 257.0 [229.0; 298.5] **
gGT (U/l) (n = 98) 30.0 [17.8; 40.5] 35.0 [26.0; 51.0] *** 21.5 [13.5; 29.0]
eGFR (ml/min) (n = 98) 78.5 [69.0; 99.0] 77.0 [69.0; 91.0] 82.5 [69.0; 102.0]
CRP (mg/l) (n = 98) 0.16 [0.07; 0.37] 0.13 [0.07; 0.27] 0.18 [0.07; 0.46]
D-dimers (μg/l) (n = 56) 75.5 [0.0; 186.3] 0.0 [0.0; 190.5] 154.0 [0.0; 179.5]

Results of physiological assessments in the 101 follow-up participants expressed as percent predicted, except for FEV1/FVC and SpO2. SpO2 = oxygen saturation from pulse oximetry, FEV1 = forced expiratory volume in 1 s, FVC = forced vital capacity, TLC = total lung capacity, RV = residual volume, 6-MWD = 6 min walk distance, LLN = lower limit of normal, ULN = upper limit of normal. Data are stratified for men and women in order to illustrate the differences. Statistical comparisons were based on the Mann-Whitney U-test or Fisher's Exact test. *p < 0.05, ** p < 0.01, *** p < 0.001.