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. 2021 Nov 24;6(12):1549–1560. doi: 10.1038/s41564-021-01000-z

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Extended Data Fig. 9 — A- Syphilis incidence per 100,000 population by year for British Columbia, (Canada) and England (UK) using currently published data. B- TPA sublineage counts for each year, using high quality genomes from British Columbia (n = 84) and England (n = 240). British Columbia samples collected from 2000-2018, English samples collected from 2012-2018. C- Pairwise comparison of SNP distance distributions from samples within and between British Columbia and England. D- Comparison of SNP distance and temporal distance within and between British Columbia and England. The plot is divided into hexagonal bins, with the colour of each hexagon representing the number of comparisons (white = none, purple = few, green = many, see scale). Linear regression lines also shown (95% CI not visible).