Figure 2.

Community antimicrobial exposure and GP practice level rates of resistance in E coli community-onset E coli bacteraemia isolates in England (2013–18)

(A) Total broad-spectrum antibiotic prescribing. (B) Total broad-spectrum antibiotic resistance. (C) Ciprofloxacin prescribing. (D) Ciprofloxacin resistance. (E) Co-amoxiclav prescribing. (F) Co-amoxiclav resistance. (G) Moxifloxacin prescribing. (H) Moxifloxacin resistance. (I) Ofloxacin prescribing. (J) Ofloxacin resistance. (K) Levofloxacin prescribing. (L) Levofloxacin resistance. Light grey shaded areas show the post-intervention period for the Quality Premium antimicrobial stewardship intervention and dark grey shaded areas show the 6-month lag period. Red lines show actual trend and red dots show the predicted trend had the Quality Premium not been implemented. GP=general practitioner.