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. 2021 Apr 8;23(4):540–548. doi: 10.1007/s12017-021-08656-0

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© The Author(s) 2021

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 3 — IL-2/IL-2R treatment enhances Tregs protection of OPCs from OGD/R. OGD/R triggered significant reduction in cell viability of OPCs but was significantly improved by IL-2/IL-2R-Treg or Treg treatment (*p < 0.0001), while IL-2/IL-2R treatment alone did not significantly improve cell survival, closely approximating that of the media control treatment group (p > 0.05). Cell viability with IL-2/IL-2R-Treg treatment was found to be significantly higher than with Treg treatment alone (*p < 0.0001)