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. 2021 Jun 14;60(12):1621–1633. doi: 10.1007/s40262-021-01039-5

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© The Author(s) 2021, corrected publication 2021

Open AccessThis article is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License, which permits any non-commercial use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by-nc/4.0/.

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Fig. 1 — Cellular kinetic model of liso-cel. C₀ initial transgene levels, C_max maximum transgene levels, F_β fraction of C_max that appears in the β or terminal phase, HL_α initial (α phase) decline half-life, HL_β terminal (β phase) half-life, T_dbl doubling time during growth phase, T_gro growth phase duration, T_lag lag phase duration, T_max time to maximum transgene levels