Table 4.
Univariate and multivariate analyses of characteristics and factors potentially associated with death or relapse within 90 days in 151 cases of E. faecalis bacteremia
| Variable | Subgroup | Mortality or recurrence of bacteraemia after 90 days | |||||
|---|---|---|---|---|---|---|---|
| Univariate analysis | Multivariate analysis | ||||||
| HR | 95% CI | p value | HR | 95% CI | p value | ||
| Sex | Male | 1 | 1 | 0.87 | |||
| Female | 0.95 | 0.52–1.75 | 0.87 | 0.95 | 0.50–1.80 | ||
| Age (years) | 1.004 | 0.99–1.03 | 0.63 | 1.01 | 0.99–1.04 | 0.30 | |
| Charlson Score ≥ 5 | 1.27 | 0.70–2.31 | 0.44 | 1.00 | 0.5–1.98 | 0.99 | |
| Severe sepsis or septic shock at onset | 4.05 | 2.30–7.15 | < 0.001 | 4.32 | 2.36–7.88 | < 0.001 | |
| Main infection focus | 0.031 | 0.027 | |||||
| Deep-seated focus | 1 | 1 | |||||
| Unknown focus | 1.004 | 0.47–2.16 | 0.99 | 1.18 | 0.49–2.82 | 0.72 | |
| Superficial focus | 0.38 | 0.17–0.86 | 0.02 | 0.33 | 0.14–0.76 | 0.009 | |
| Mode of acquisition | 0.44 | 0.19 | |||||
| Community-acquired | 1 | 1 | |||||
| Hospital-acquired | 1.31 | 0.66–2.61 | 0.43 | 1.37 | 0.62–3.01 | 0.44 | |
| Healthcare-associated | 1.64 | 0.76–3.51 | 0.20 | 2.14 | 0.92–5.00 | 0.08 | |
| ID specialist consultation | 0.92 | 0.49–1.73 | 0.80 | 0.87 | 0.45–1.66 | 0.66 | |
IDC is expressed as time-dependent covariable